Wellington Case Report: Spine infection 3 months post PLIF

DISCHARGE SUMMARY

A.D, 58 YEARS, MALE, 

 

Diagnosis: spine infection 3 months post PLIF

Treatment: Non operative (antibiotics)

Background Presenting Information:

The above-named patient is a known patient of this facility; He had a L5/S1 posterior lumbar interbody fusion on account of L5/S1 degenerative disc disease about 3 months ago. He subsequently developed surgical site collection of hematoma and serosanguinous fluid which required wound washout twice before complete wound healing. He has enjoyed a relatively uneventful recuperation following discharge 2 months ago.

However, he represented on the 13/01/2023 with complains of  sudden onset radicular low back pains, following some domestic exertion, and associated with fever, headache, generalized weakness and difficulty in walking. He describes the pain as sharp, constant, aggravated by sitting and walking. Pain was severe - VAS score of 9.

Admitting vital signs: PR: 104B/M BP: 150/100mmhg, RR: 24C/M, Spo2:94%RA

On examination: in moderate painful distress, not pale, anicteric, febrile (39.0), previous scar seen on midline of the back. Full power in lower limbs, normal bowel and bladder functions. Previous midline lumbar spine scar was noted to have healed completely, with no evidence of discharge or swelling but exquisitely tender on deep palpation and differential warmth.

Blood Investigations on admission - 14/01/2023 suggest clearly an inflammatory process on going

·         FBC – WBC- 15.12, PCV-38 %, PLT- 313.

·         MP: positive

·         CRP: > 200

Imaging – L/S CT scan done (14/01/2023) showed L5/S1 screws  and intervening cage in place with no evidence of instability(See image below)



  MRI(L/S)  16/01/2023 below did not show any convincing evidence of paraspinal abscess but obvious post surgical changes

  

 

Based on the above clinical, laboratory and imaging findings, a late onset paraspinal inflammation was suspected but to rule out any infection. And he was placed on the following medications immediately

·         IM emal 150mg dly for 3 days

·         IV rocephin 1G 12hrly for 2 weeks

·         IV vancomycin 750mg 8hrly for 2 weeks

·         IV tramadol 50mg 12hrly x 72hrs

·         IV PCM 600mg 8hrly x 72hrs

·         Supp diclofenac 100mg 12hrly x 1 week

·         Tab Omeprazole 20mg bd x 1/52

·         IV pentidine 50mg PRN

·         Tabs lyrica 75mg 12hrly

 

Follow up Lab Investigations: 16/01/2023 reveals that CRP is still significantly high but the WBC was on decline. He was to continue the IV antibiotics for at least two weeks and then to switch over to oral antibiotics for another 4 weeks.

FBC: WBC: 11.25, PCV: 38% PLT: 198

CRP: > 200Mg/l

EUCR: Na: 136.7, K: 3.8, CL: 108 Urea: 21, Creatinine: 0.36

Lab Investigations : 20/01/2023

CRP: > 200 mg/l

Lab Investigations: 23/01/2023

FBC: WBC: 12.1 PCV: 38.9 PLT: 470

CRP: 127 Mg/l

EUCR: Na: 140 K: 4.92 CL: 107.8 CR: 0.61 Urea: 39.75

 

Update 30/01/2023

Following the completion of 14days of IV Vancomycin and IV Rocephin today his clinical condition improved although was still having mild intermittent fever. Inflammatory markers showed reduction from previously elevated values. CRP was noted on the down ward trend. He was not quite ambulant and tolerating physiotherapy much better. He will continue tab Zinnat 500mg bd for another 4 weeks

Lab Investigations: 30/01/2023

FBC: WBC: 6.71 PCV: 40.02 PLT: 282

EUCR: Na: 139 K: 4.46 CL: 107.2 Urea:19.37 Cr: 0.72

CRP: 107mg/l

 

A check L/S MRI 30/01/2023 still did not reveal any evidence of paraspinal abscess


   


T1 SAG with CONTRAST      T2 SAG WITHOUT CONTRAST    

MRI L/S done revealed no ring enhancing lesion on the contrasted T1 SAG view

 Update (01/02/2023)

Clinically, he has improved significantly as low back pain has reduced and he is currently walking without much difficulty.

MRI L/S showed reducing inflammation compared to previous MRI done on the 16/01/2023 and no obvious sign of abscess collection.

CRP, FBC, inflammatory markers which were previous elevated has been on the downward trend.

He is to continue Tab Zinnat 500mg bd for the next 4 weeks, serial blood test and for possible discharge. It is however recommended that he should not return to Makurdi just yet due to probable uncomfortable bad roads, long journey time and the overwhelming need for him to stay closer to the hospital for ease of access to follow up visits until the expiry of his treatments in about 4 weeks. A nearby apartment or Hotel is highly recommended for your considerations  and please contact us again for any further clarifications.

Discharge medications:

·         Tabs Zinnat 500mg twice daily for 3 weeks

·         Tabs lyrica 150mg dly

·         Tabs chymoral 2 tablets three times daily for 3 days

·         Tabs vitamin c 1000mg twice daily for 9 days

 

Discharge instructions

·         Should have adequate rest and avoid strenuous activities

·         Regular light exercises

·         Healthy lifestyle and drink about 3 liters of water in a day.

 

UPDATE (6/04/2023)

Continued to have back and leg pain. Shocking in nature and marginal relieve with neuropathic medications. Seal dose of gabapentin. Still has low back and waist pains but normal full power both upper and lower limbs. Normal bowel and bladder functions.

Check CT lumbosacral spine shows implant in place but S1 implant (pedicle screws) seen to have a halo around the distal half. Most importantly, the healing and fusion progess is satisfactory but it appears as though he is reacting to or not tolerating the implant. Therefore, need to review with a view to remove the implant when healing is very satisfactory and discuss with the patient.

Plan:

·         Tabs Zinnat 500mg bd x 1/12

·         To see in four weeks time.

 

Dr Oseni Somina  MD

 

For Team Wellington Clinics Abuja

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09 Oct, 2023
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